You're reading the documentation for a development version. For the latest released version, please have a look at v5.0.1.

Generalized Ion Exchange

Group /input/model/unit_XXX/adsorption – ADSORPTION_MODEL = GENERALIZED_ION_EXCHANGE

For information on model equations, refer to Generalized Ion Exchange.

IS_KINETIC

Selects kinetic or quasi-stationary adsorption mode: 1 = kinetic, 0 = quasi-stationary. If a single value is given, the mode is set for all bound states. Otherwise, the adsorption mode is set for each bound state separately.

Type: int

Range: {0,1}

Length: 1/NTOTALBND
GIEX_KA

Base value of adsorption rate constant

Unit: \(m_{MP}^{3}~m_{SP}^{-3}~s^{-1}\)

Type: double

Range: \(\ge 0\)

Length: NCOMP
GIEX_KA_LIN

Coefficient of linear dependence of adsorption rate constant on modifier component

Unit: \(\text{[Mod]}^{-1}\)

Type: double

Length: NCOMP
GIEX_KA_QUAD

Coefficient of quadratic dependence of adsorption rate constant on modifier component

Unit: \(\text{[Mod]}^{-2}\)

Type: double

Length: NCOMP
GIEX_KA_SALT

Salt coefficient of adsorption rate constants; difference of water-protein and salt-protein interactions

Type: double

Length: NCOMP
GIEX_KA_PROT

Protein coefficient of adsorption rate constants; difference of water-protein and protein-protein interactions

Unit: \(m_{MP}^{3} mol^{-1}\)

Type: double

Length: NCOMP
GIEX_KD

Base value of desorption rate constant

Unit: \(s^{-1}\)

Type: double

Range: \(\ge 0\)

Length: NCOMP
GIEX_KD_LIN

Coefficient of linear dependence of desorption rate constant on modifier component

Unit: \(\text{[Mod]}^{-1}\)

Type: double

Length: NCOMP
GIEX_KD_QUAD

Coefficient of quadratic dependence of desorption rate constant on modifier component

Unit: \(\text{[Mod]}^{-2}\)

Type: double

Length: NCOMP
GIEX_KD_SALT

Salt coefficient of desorption rate constants; difference of water-protein and salt-protein interactions

Type: double

Length: NCOMP
GIEX_KD_PROT

Protein coefficient of desorption rate constants; difference of water-protein and protein-protein interactions

Unit: \(m_{MP}^{3} mol^{-1}\)

Type: double

Length: NCOMP
GIEX_NU

Base value for characteristic charges of the protein; The number of sites \(\nu\) that the protein interacts with on the resin surface

Type: double

Length: NCOMP
GIEX_NU_LIN

Coefficient of linear dependence of characteristic charge on modifier component

Unit: \(\text{[Mod]}^{-1}\)

Type: double

Length: NCOMP
GIEX_NU_QUAD

Coefficient of quadratic dependence of characteristic charge on modifier component

Unit: \(\text{[Mod]}^{-2}\)

Type: double

Length: NCOMP
GIEX_SIGMA

Steric factors of the protein; The number of sites \(\sigma\) on the surface that are shielded by the protein and prevented from exchange with the salt counterions in solution

Type: double

Range: \(\ge 0\)

Length: NCOMP
GIEX_LAMBDA

Stationary phase capacity (monovalent salt counterions); The total number of binding sites available on the resin surface

Unit: \(mol~m_{SP}^{-3}\)

Type: double

Range: \(\ge 0\)

Length: 1
GIEX_REFC0

Reference liquid phase concentration (optional, defaults to \(1.0\))

Unit: \(mol~m_{MP}^{-3}\)

Type: double

Range: \(\gt 0\)

Length: 1
GIEX_REFQ

Reference solid phase concentration (optional, defaults to \(1.0\))

Unit: \(mol~m_{SP}^{-3}\)

Type: double

Range: \(\gt 0\)

Length: 1