Generalized Ion Exchange¶
Group /input/model/unit_XXX/adsorption – ADSORPTION_MODEL = GENERALIZED_ION_EXCHANGE
IS_KINETIC
Selects kinetic or quasi-stationary adsorption mode: 1 = kinetic, 0 = quasi-stationary. If a single value is given, the mode is set for all bound states. Otherwise, the adsorption mode is set for each bound state separately.
Type: int |
Range: {0,1} |
Length: 1/NTOTALBND |
GIEX_KA
Base value of adsorption rate constant
Unit: \(m_{MP}^{3}~m_{SP}^{-3}~s^{-1}\)
Type: double |
Range: \(\ge 0\) |
Length: NCOMP |
GIEX_KA_LIN
Coefficient of linear dependence of adsorption rate constant on modifier component
Unit: \(\text{[Mod]}^{-1}\)
Type: double |
Length: NCOMP |
GIEX_KA_QUAD
Coefficient of quadratic dependence of adsorption rate constant on modifier component
Unit: \(\text{[Mod]}^{-2}\)
Type: double |
Length: NCOMP |
GIEX_KA_SALT
Salt coefficient of adsorption rate constants; difference of water-protein and salt-protein interactions
Type: double |
Length: NCOMP |
GIEX_KA_PROT
Protein coefficient of adsorption rate constants; difference of water-protein and protein-protein interactions
Unit: \(m_{MP}^{3} mol^{-1}\)
Type: double |
Length: NCOMP |
GIEX_KD
Base value of desorption rate constant
Unit: \(s^{-1}\)
Type: double |
Range: \(\ge 0\) |
Length: NCOMP |
GIEX_KD_LIN
Coefficient of linear dependence of desorption rate constant on modifier component
Unit: \(\text{[Mod]}^{-1}\)
Type: double |
Length: NCOMP |
GIEX_KD_QUAD
Coefficient of quadratic dependence of desorption rate constant on modifier component
Unit: \(\text{[Mod]}^{-2}\)
Type: double |
Length: NCOMP |
GIEX_KD_SALT
Salt coefficient of desorption rate constants; difference of water-protein and salt-protein interactions
Type: double |
Length: NCOMP |
GIEX_KD_PROT
Protein coefficient of desorption rate constants; difference of water-protein and protein-protein interactions
Unit: \(m_{MP}^{3} mol^{-1}\)
Type: double |
Length: NCOMP |
GIEX_NU
Base value for characteristic charges of the protein; The number of sites \(\nu\) that the protein interacts with on the resin surface
Type: double |
Length: NCOMP |
GIEX_NU_LIN
Coefficient of linear dependence of characteristic charge on modifier component
Unit: \(\text{[Mod]}^{-1}\)
Type: double |
Length: NCOMP |
GIEX_NU_QUAD
Coefficient of quadratic dependence of characteristic charge on modifier component
Unit: \(\text{[Mod]}^{-2}\)
Type: double |
Length: NCOMP |
GIEX_SIGMA
Steric factors of the protein; The number of sites \(\sigma\) on the surface that are shielded by the protein and prevented from exchange with the salt counterions in solution
Type: double |
Range: \(\ge 0\) |
Length: NCOMP |
GIEX_LAMBDA
Stationary phase capacity (monovalent salt counterions); The total number of binding sites available on the resin surface
Unit: \(mol~m_{SP}^{-3}\)
Type: double |
Range: \(\ge 0\) |
Length: 1 |
GIEX_REFC0
Reference liquid phase concentration (optional, defaults to \(1.0\))
Unit: \(mol~m_{MP}^{-3}\)
Type: double |
Range: \(\gt 0\) |
Length: 1 |
GIEX_REFQ
Reference solid phase concentration (optional, defaults to \(1.0\))
Unit: \(mol~m_{SP}^{-3}\)
Type: double |
Range: \(\gt 0\) |
Length: 1 |