.. _generalized_ion_exchange_config:

Generalized Ion Exchange
~~~~~~~~~~~~~~~~~~~~~~~~

**Group /input/model/unit_XXX/adsorption – ADSORPTION_MODEL = GENERALIZED_ION_EXCHANGE**

For information on model equations, refer to :ref:`generalized_ion_exchange_model`.


``IS_KINETIC``
   Selects kinetic or quasi-stationary adsorption mode: 1 = kinetic, 0 =
   quasi-stationary. If a single value is given, the mode is set for all
   bound states. Otherwise, the adsorption mode is set for each bound
   state separately.

===================  =========================  =========================================
**Type:** int        **Range:** {0,1}  		**Length:** 1/NTOTALBND
===================  =========================  =========================================

``GIEX_KA``
   Base value of adsorption rate constant

**Unit:** :math:`m_{MP}^{3}~m_{SP}^{-3}~s^{-1}`

===================  =========================  =========================================
**Type:** double     **Range:** :math:`\ge 0`   **Length:** NCOMP
===================  =========================  =========================================

``GIEX_KA_LIN``
   Coefficient of linear dependence of adsorption rate constant on
   modifier component

**Unit:** :math:`\text{[Mod]}^{-1}`

===================  =========================  
**Type:** double     **Length:** NCOMP
===================  ========================= 

``GIEX_KA_QUAD``
   Coefficient of quadratic dependence of adsorption rate constant on
   modifier component

**Unit:** :math:`\text{[Mod]}^{-2}`

===================  =========================  
**Type:** double     **Length:** NCOMP
===================  ========================= 

``GIEX_KA_SALT``
   Salt coefficient of adsorption rate constants; difference of
   water-protein and salt-protein interactions

===================  =========================  
**Type:** double     **Length:** NCOMP
===================  ========================= 

``GIEX_KA_PROT``
   Protein coefficient of adsorption rate constants; difference of
   water-protein and protein-protein interactions

**Unit:** :math:`m_{MP}^{3} mol^{-1}`

===================  =========================  
**Type:** double     **Length:** NCOMP
===================  ========================= 

``GIEX_KD``
   Base value of desorption rate constant

**Unit:** :math:`s^{-1}`

===================  =========================  =========================================
**Type:** double     **Range:** :math:`\ge 0`   **Length:** NCOMP
===================  =========================  =========================================

``GIEX_KD_LIN``
   Coefficient of linear dependence of desorption rate constant on
   modifier component

**Unit:** :math:`\text{[Mod]}^{-1}`

===================  =========================  
**Type:** double     **Length:** NCOMP
===================  ========================= 

``GIEX_KD_QUAD``
   Coefficient of quadratic dependence of desorption rate constant on
   modifier component

**Unit:** :math:`\text{[Mod]}^{-2}`

===================  =========================  
**Type:** double     **Length:** NCOMP
===================  ========================= 

``GIEX_KD_SALT``
   Salt coefficient of desorption rate constants; difference of
   water-protein and salt-protein interactions

===================  =========================  
**Type:** double     **Length:** NCOMP
===================  ========================= 

``GIEX_KD_PROT``
   Protein coefficient of desorption rate constants; difference of
   water-protein and protein-protein interactions

**Unit:** :math:`m_{MP}^{3} mol^{-1}`

===================  =========================  
**Type:** double     **Length:** NCOMP
===================  ========================= 

``GIEX_NU``
   Base value for characteristic charges of the protein; The number of
   sites :math:`\nu` that the protein interacts with on the resin
   surface

===================  =========================  
**Type:** double     **Length:** NCOMP
===================  ========================= 

``GIEX_NU_LIN``
   Coefficient of linear dependence of characteristic charge on modifier
   component

**Unit:** :math:`\text{[Mod]}^{-1}`

===================  =========================  
**Type:** double     **Length:** NCOMP
===================  ========================= 

``GIEX_NU_QUAD``
   Coefficient of quadratic dependence of characteristic charge on
   modifier component

**Unit:** :math:`\text{[Mod]}^{-2}`

===================  =========================  
**Type:** double     **Length:** NCOMP
===================  ========================= 

``GIEX_SIGMA``
   Steric factors of the protein; The number of sites :math:`\sigma` on
   the surface that are shielded by the protein and prevented from
   exchange with the salt counterions in solution

===================  =========================  =========================================
**Type:** double     **Range:** :math:`\ge 0`   **Length:** NCOMP
===================  =========================  =========================================

``GIEX_LAMBDA``
   Stationary phase capacity (monovalent salt counterions); The total
   number of binding sites available on the resin surface

**Unit:** :math:`mol~m_{SP}^{-3}`

===================  =========================  =========================================
**Type:** double     **Range:** :math:`\ge 0`   **Length:** 1
===================  =========================  =========================================

``GIEX_REFC0``
   Reference liquid phase concentration (optional, defaults to
   :math:`1.0`)

**Unit:** :math:`mol~m_{MP}^{-3}`

===================  =========================  =========================================
**Type:** double     **Range:** :math:`\gt 0`   **Length:** 1
===================  =========================  =========================================

``GIEX_REFQ``
   Reference solid phase concentration (optional, defaults to
   :math:`1.0`)

**Unit:** :math:`mol~m_{SP}^{-3}`

===================  =========================  =========================================
**Type:** double     **Range:** :math:`\gt 0`   **Length:** 1
===================  =========================  =========================================